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Description

The conversation around GLP-1 medicines was no longer only about diabetes

GLP-1RAs such as liraglutide and exenatide decrease pro-inflammatory cytokines, tumor necrosis factor-alpha ( TNF- ), and interleukin-1 (IL-18) in rodent mouse models of diabetic neuropathy [69,70]

GLP-1 is an endogenous incretin hormone produced by intestinal enteroendocrine L-cells following nutrient ingestion [6]

A challenge with developing a more effective pill has been how to improve its bioavailabilitythe amount of drug that enters circulation and has an active effect

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